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bp0005rdr14 | Pre-natal Programming of Lifetime Productivity and Health | REDR2002

Ruminant models of prenatal growth restriction

Anthony RV , Scheaffer AN , Wright CD , Regnault TRH

Intrauterine growth restriction (IUGR) is a significant health issue that not only affects infant mortality and morbidity, but may also predispose individuals to coronary heart disease, diabetes, hypertension and stroke as adults. The majority of IUGR pregnancies in humans are characterized by asymmetric fetal growth, resulting from inadequate nutrient transfer to the fetus. Furthermore, most of these pregnancies involve functional placental insufficiency, and may also show al...